Unlike most Care Bear villains, Grizzle appears to have been a Care Bear himself who turned evil by choice. He is also the first villain who is a bear. He is the main antagonist of the series.
He is an orange-brown bear of short stature, but wears a large metal exoskeleton. The fur on his head is rather messy and ragged, almost mohawk-like. His most notable feature is his elongated, oversized head.
He is an inventor who has created his metal exoskeleton, several robots, and commands an army of robot mice.
Unlike Grumpy Bear, whose inventions are well-intended, Grizzle seeks to use his own inventions and creations to disrupt the lives of the Care Bears, and if possible, destroy Care-a-Lot as well. Grizzle often yells and is rude to his robot assistants, UR2 and Sargent Rocketbottom. He is often seen trying to create inventions to rid the world of Care-a-Lot, but they always end up failing.
He is portrayed as comical villain rather than a menacing one, and is easily defeated despite his persistence.